​よつば:

 

This is the name of the main character.

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When literally translated, the name "Yotsuba" (四葉) means "four leaves", as in "yotsuba no kuroubaa" (四葉のクローバー), which means "four-leaf clover".

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Observing her green hair which is always styled into four pigtails, the author's reason to choose such name becomes evident.